Hoe kunnen we de overgang maken van evidence-based medicine naar personalized (of mechanism-based) medicine: welke onderzoeksmethoden hebben we hiervoor nodig?
The organization of healthcare is in a state of transition. Shortcomings in the present delivery of healthcare as well as novel developments in definition of health, technology, patient participation and society urge the development and implementation of new concepts of healthcare delivery. This complex endeavor is only possible, when a sound scientific base is present. At present, patients experience large variation in quality, safety and costs of healthcare. An abundance of literature shows that evidence based medicine doesn’t reach all patients on time or at different places.